Research
BPC-157
A synthetic chain of 15 amino acids, corresponding to a partial sequence of a protein found in human gastric juice.
Available in the catalogue
Supplied as research material. Sizes and pricing are on the product page. Availability is not a statement about what a compound does.
What is being investigated
Directions the published work points at, and how far each has actually got. These are open questions, not established effects: most of what looks promising in cells does not replicate in animals, and most of what works in animals does not work in people. Nothing here is a claim about what this compound does for anyone.
- Tendon, ligament and muscle repair
The largest part of its literature. Rat models of transected tendon and ligament ask whether repair proceeds faster and holds better, assessed functionally, biomechanically and histologically. Every one of those studies is in an animal.
Animal studies
- Gastrointestinal mucosal protection
Where the molecule came from — it was carried into early human trials as PL 14736 for inflammatory bowel disease. The published record of that programme is thin, and it is the only human work there is.
Human trials
- Angiogenesis
Formation of new blood vessels is the mechanism most often proposed to sit underneath the repair findings, and is studied directly in animal and cell work rather than only inferred from them.
Animal studies Cell and tissue studies
- Nerve and vascular recovery
Rodent models of nerve crush and of vessel occlusion ask whether the same effects extend beyond soft tissue. A wide preclinical literature from a small number of groups, which is worth weighing.
Animal studies
Published research
Every reference below was checked against the published record before being listed, with the model each study used.
- Chang et al. (2011)Journal of Applied Physiology · 110(3):774–80
Reported increased outgrowth of tendon fibroblasts from explanted tissue, improved survival under oxidative stress, and increased cell migration.
in vitro, cultured rat Achilles tendon cells Source
- Cerovecki et al. (2010)Journal of Orthopaedic Research
Reported improved healing of surgically transected medial collateral ligament over 90 days, assessed functionally, biomechanically and histologically.
rat Source
Further reading
Longer articles on handling, analysis and what the published work reports.
- BPC-157: what the research says
Body Protection Compound 157 has a large rodent literature and almost no human data. What the studies measured, in which models, and the caveat behind them.
- How to store research peptides
Lyophilised peptides at -20°C, reconstituted at 2–8°C, ambient in transit. Why the dry cake tolerates shipping, and what actually degrades a vial.
- Peptide shelf life and stability
How long lyophilised and reconstituted peptides keep, and the four things that shorten it: temperature, moisture, light and oxidation. Storage figures included.
- How to reconstitute lyophilised peptides
How to reconstitute a lyophilised peptide with bacteriostatic water without damaging it: why you run the liquid down the vial wall and never shake it.