Research
Epitalon
A four-amino-acid peptide whose sequence was derived from epithalamin, a preparation extracted from the pineal gland.
Available in the catalogue
Supplied as research material. Sizes and pricing are on the product page. Availability is not a statement about what a compound does.
What is being investigated
Directions the published work points at, and how far each has actually got. These are open questions, not established effects: most of what looks promising in cells does not replicate in animals, and most of what works in animals does not work in people. Nothing here is a claim about what this compound does for anyone.
- Telomerase activation and telomere length
Reported induction of telomerase activity and telomere elongation in cultured human fibroblasts, with extension of their replicative lifespan. From one group, and that qualification applies to everything on this list.
Cell and tissue studies
- Lifespan and tumour incidence in rodents
The animal work the group published alongside the cell studies. Rodent lifespan studies are the point at which most ageing hypotheses either survive or stop, and independent replication is what they have not had.
Animal studies
- Pineal function and circadian rhythm
The sequence came from a pineal extract, and part of the literature follows that origin into melatonin rhythm rather than into telomeres.
Animal studies
- Whether telomere length is worth lengthening
The open question above all of it, and it is not about this peptide. Telomere shortening tracks ageing; whether reversing it is beneficial, neutral or a cancer risk is unresolved in the field generally.
Proposed from mechanism
Published research
Every reference below was checked against the published record before being listed, with the model each study used.
- Khavinson et al. (2003)Bulletin of Experimental Biology and Medicine
Reported induction of telomerase activity and telomere elongation in human somatic cells in culture.
in vitro, cultured human fibroblasts Source
Further reading
Longer articles on handling, analysis and what the published work reports.
- Epitalon (Epithalon, AEDG): what the research says
A tetrapeptide investigated for telomerase activity, with a literature long dominated by one institute — and a recent independent replication worth reading.
- How to store research peptides
Lyophilised peptides at -20°C, reconstituted at 2–8°C, ambient in transit. Why the dry cake tolerates shipping, and what actually degrades a vial.
- Peptide shelf life and stability
How long lyophilised and reconstituted peptides keep, and the four things that shorten it: temperature, moisture, light and oxidation. Storage figures included.
- How to reconstitute lyophilised peptides
How to reconstitute a lyophilised peptide with bacteriostatic water without damaging it: why you run the liquid down the vial wall and never shake it.