Research

HCG

A glycoprotein hormone of two subunits, produced by the placenta during pregnancy. Its alpha subunit is shared with LH, FSH and TSH; the beta subunit is what makes it distinct.

Also published as: Human chorionic gonadotropin · Choriogonadotropin alfa

Available in the catalogue

Supplied as research material. Sizes and pricing are on the product page. Availability is not a statement about what a compound does.

  • HCG

    Hormonal & Reproductive

What is being investigated

Directions the published work points at, and how far each has actually got. These are open questions, not established effects: most of what looks promising in cells does not replicate in animals, and most of what works in animals does not work in people. Nothing here is a claim about what this compound does for anyone.

  1. Ovulation induction

    Its established clinical use, with decades of controlled work behind it. Nothing here is new or speculative, which makes this the best-evidenced entry in the catalogue rather than the most interesting one.

    Human trials

  2. Testicular function in male hypogonadism

    Binding the LH receptor stimulates the cells that produce sex steroids directly, which is why it appears in trials of preserving testicular function and spermatogenesis alongside testosterone therapy.

    Human trials

  3. Weight loss

    The one worth stating plainly: the widely promoted 'HCG diet' has been tested in randomised placebo-controlled trials and did not outperform placebo. This is a settled negative result, not an open question.

    Human trials Did not work

Published research

Every reference below was checked against the published record before being listed, with the model each study used.

  1. Singhania et al. (2024)Endocrine Practice · 30(10):978–86

    Compared a combined low-dose gonadotropin and testosterone regimen against a conventional higher-dose regimen in hypogonadal men.

    human, comparative clinical study Source

  2. Zheng et al. (2025)Reproductive Biology and Endocrinology · 23(1):46

    Compared spermatogenesis outcomes between pulsatile GnRH and combined gonadotropin therapy in congenital hypogonadotropic hypogonadism.

    human, comparative clinical study Source

Further reading

Longer articles on handling, analysis and what the published work reports.

  • HCG chorionic gonadotropin: what the research says

    A long-established fertility medicine, and a literature that is almost entirely about treating diagnosed endocrine deficiency. Not about weight loss.

  • How to store research peptides

    Lyophilised peptides at -20°C, reconstituted at 2–8°C, ambient in transit. Why the dry cake tolerates shipping, and what actually degrades a vial.

  • Peptide shelf life and stability

    How long lyophilised and reconstituted peptides keep, and the four things that shorten it: temperature, moisture, light and oxidation. Storage figures included.

  • How to reconstitute lyophilised peptides

    How to reconstitute a lyophilised peptide with bacteriostatic water without damaging it: why you run the liquid down the vial wall and never shake it.

All compounds