Research
Hexarelin
A synthetic hexapeptide analogue of GHRP-6, modified for greater potency and stability.
Available in the catalogue
Supplied as research material. Sizes and pricing are on the product page. Availability is not a statement about what a compound does.
What is being investigated
Directions the published work points at, and how far each has actually got. These are open questions, not established effects: most of what looks promising in cells does not replicate in animals, and most of what works in animals does not work in people. Nothing here is a claim about what this compound does for anyone.
- Growth hormone release in humans
Dose-dependent release was reported in healthy volunteers in rising-dose work. Whether repeated exposure sustains it is a separate question, and desensitisation on continued administration is what stalled its clinical development.
Human trials
- Cardiac protection through CD36
Whether the receptor it binds in heart tissue — distinct from the one driving growth hormone release — protects myocardium under ischaemic stress. Studied in rodent models, and the reason a cardiovascular literature exists for it at all.
Animal studies
- Muscle wasting
Among the more potent secretagogues studied in people, which is the stated rationale for looking at it in catabolic states. The rationale is not itself a result.
Proposed from mechanism
Published research
Every reference below was checked against the published record before being listed, with the model each study used.
- Imbimbo et al. (1994)European Journal of Clinical Pharmacology · 46(5):421–5
Reported dose-dependent growth hormone release in healthy male volunteers across a range of hexarelin doses.
human, double-blind placebo-controlled rising-dose Source
Further reading
Longer articles on handling, analysis and what the published work reports.
- Hexarelin (examorelin): what the research says
One of the most potent secretagogues tested in humans, with a second cardiac literature running through CD36 rather than the growth hormone axis.
- How to store research peptides
Lyophilised peptides at -20°C, reconstituted at 2–8°C, ambient in transit. Why the dry cake tolerates shipping, and what actually degrades a vial.
- Peptide shelf life and stability
How long lyophilised and reconstituted peptides keep, and the four things that shorten it: temperature, moisture, light and oxidation. Storage figures included.
- How to reconstitute lyophilised peptides
How to reconstitute a lyophilised peptide with bacteriostatic water without damaging it: why you run the liquid down the vial wall and never shake it.