Research
Selank
A seven-amino-acid peptide built from tuftsin, a fragment of an immunoglobulin heavy chain, again with a Pro-Gly-Pro tail for stability.
Available in the catalogue
Supplied as research material. Sizes and pricing are on the product page. Availability is not a statement about what a compound does.
What is being investigated
Directions the published work points at, and how far each has actually got. These are open questions, not established effects: most of what looks promising in cells does not replicate in animals, and most of what works in animals does not work in people. Nothing here is a claim about what this compound does for anyone.
- Generalised anxiety
The indication behind its Russian registration, including comparisons against benzodiazepines. As with Semax, that literature is mostly in Russian and mostly from the institutions that developed the compound.
Human trials
- Anxiolysis without sedation
The property that drew attention in the animal work: activity in maze models without the sedation and motor impairment benzodiazepines produce. It is a claim about what is absent, which is harder to establish than one about what is present.
Animal studies
- GABAergic and serotonergic signalling
The proposed mechanism, examined in vitro and in rodents, alongside reported effects on BDNF expression.
Animal studies Cell and tissue studies
Published research
Every reference below was checked against the published record before being listed, with the model each study used.
- Vyunova et al. (2018)Protein and Peptide Letters · 25(10):914–23
A review of the molecular basis of the peptide's reported anxiolytic activity, covering its interaction with GABAergic signalling and its effects on BDNF expression.
review of in vitro and rodent work Source
Further reading
Longer articles on handling, analysis and what the published work reports.
- Selank (TP-7): what the research says
A tuftsin-derived anxiolytic registered as a medicine in Russia. Its defining reported property is what it lacks: sedation. The rodent evidence, and the limits.
- How to store research peptides
Lyophilised peptides at -20°C, reconstituted at 2–8°C, ambient in transit. Why the dry cake tolerates shipping, and what actually degrades a vial.
- Peptide shelf life and stability
How long lyophilised and reconstituted peptides keep, and the four things that shorten it: temperature, moisture, light and oxidation. Storage figures included.
- How to reconstitute lyophilised peptides
How to reconstitute a lyophilised peptide with bacteriostatic water without damaging it: why you run the liquid down the vial wall and never shake it.