Research
Sermorelin
The first 29 amino acids of human growth hormone-releasing hormone — the shortest fragment that retains the full activity of the natural hormone.
Available in the catalogue
Supplied as research material. Sizes and pricing are on the product page. Availability is not a statement about what a compound does.
What is being investigated
Directions the published work points at, and how far each has actually got. These are open questions, not established effects: most of what looks promising in cells does not replicate in animals, and most of what works in animals does not work in people. Nothing here is a claim about what this compound does for anyone.
- Diagnosis of growth hormone deficiency
Its best-established use in the published clinical literature: a test of whether a pituitary can release growth hormone when the GHRH receptor is stimulated.
Human trials
- Paediatric growth hormone deficiency
Reviewed in children with idiopathic deficiency, where the question is whether stimulating the pituitary reaches what administered growth hormone reaches.
Human trials
- Age-related decline in growth hormone output
Growth hormone falls with age and GHRH analogues act upstream of that decline, which is the stated reason for interest. Whether restoring the signal changes anything a person would notice is not a question the published trials were designed to answer.
Proposed from mechanism
Published research
Every reference below was checked against the published record before being listed, with the model each study used.
- Prakash & Goa (1999)BioDrugs
A review of sermorelin in the diagnosis and treatment of children with idiopathic growth hormone deficiency.
review of human clinical use Source
Further reading
Longer articles on handling, analysis and what the published work reports.
- Sermorelin (GHRH 1-29): what the research says
A former prescription medicine sold as Geref. The clinical evidence is in children with growth hormone deficiency, and it does not transfer to healthy adults.
- How to store research peptides
Lyophilised peptides at -20°C, reconstituted at 2–8°C, ambient in transit. Why the dry cake tolerates shipping, and what actually degrades a vial.
- Peptide shelf life and stability
How long lyophilised and reconstituted peptides keep, and the four things that shorten it: temperature, moisture, light and oxidation. Storage figures included.
- How to reconstitute lyophilised peptides
How to reconstitute a lyophilised peptide with bacteriostatic water without damaging it: why you run the liquid down the vial wall and never shake it.